ORIGINAL PAPER
Effects of polarised, sprint interval, high-intensity interval, and low-intensity training programs on aerobic fitness and cardiovascular health markers in active individuals
1
Department of Physiology and Biochemistry, Wroclaw University of Health and Sport Sciences, Wroclaw, Poland
2
Department of Human, Society and Health Sciences, University of Cassino and Lazio Meridionale, Cassino, Frosinone, Italy
Submission date: 2023-09-18
Acceptance date: 2024-04-02
Publication date: 2024-06-28
Corresponding author
Paulina Hebisz
Wroclaw University of Health and Sport Sciences, Wroclaw, Poland Department of Physiology and Biochemistry
Wroclaw University of Health and Sport Sciences, Wroclaw, Poland Department of Physiology and Biochemistry
Hum Mov. 2024;25(2):86-96
KEYWORDS
cardiorespiratory fitnesscardiovascular healthmaximal aerobic poweroxidative stressmaximal oxygen uptake
TOPICS
ABSTRACT
Purpose:
This study aimed to assess the impact of four distinct training programs on maximal oxygen uptake (VO2max) and cardiovascular health markers. The programs included: 1) a polarised training program (POL) incorporating sprint interval training (SIT), high-intensity interval training (HIIT) with long intervals, and low-intensity training (LIT); 2) a program focused solely on SIT training; 3) a program focused solely on long interval HIIT training; and 4) a program focused solely on LIT. The outcomes of interest were VO2max, lectin-like oxidised low-density lipoprotein receptor-1 (LOX-1) expression, and serum concentration of oxidised low-density lipoprotein (ox-LDL).
Methods:
This study enrolled 40 physically active individuals, categorised into four groups. Group POL (n = 10) engaged in a comprehensive POL training program, while group SIT (n = 10), group HIIT (n = 10), and group LIT (n = 10) participated in dedicated SIT, HIIT, and LIT training programs, respectively. SIT included 30-second all-out repetitions, HIIT included 3-minute high-intensity repetitions, LIT performed with intensity at the first ventilatory threshold. Throughout five weeks, participants in all groups underwent three weekly training sessions. Preceding and following the experiment, participants underwent an incremental test and a VO2max verification test. Additionally, serum concentrations of lectin-like oxidised lowdensity lipoprotein receptor-1 (LOX-1) and oxidised low-density lipoprotein (ox-LDL) were measured before the incremental test.
Results:
Following the conclusion of the experiment, notable mixed effects were observed. Specifically, statistically significant increases were identified in VO2max, with a 14.2% enhancement in the POL group and a 9.5% improvement in the HIIT group. Moreover, there were substantial reductions in LOX-1 levels, demonstrating a 51.5% decrease in the POL group and a 61.1% decrease in the HIIT group.
Conclusions:
The findings led to the conclusion that both the POL and long interval HIIT programs were effective in enhancing VO2max and lowering serum levels of LOX-1 among physically active individuals.
This study aimed to assess the impact of four distinct training programs on maximal oxygen uptake (VO2max) and cardiovascular health markers. The programs included: 1) a polarised training program (POL) incorporating sprint interval training (SIT), high-intensity interval training (HIIT) with long intervals, and low-intensity training (LIT); 2) a program focused solely on SIT training; 3) a program focused solely on long interval HIIT training; and 4) a program focused solely on LIT. The outcomes of interest were VO2max, lectin-like oxidised low-density lipoprotein receptor-1 (LOX-1) expression, and serum concentration of oxidised low-density lipoprotein (ox-LDL).
Methods:
This study enrolled 40 physically active individuals, categorised into four groups. Group POL (n = 10) engaged in a comprehensive POL training program, while group SIT (n = 10), group HIIT (n = 10), and group LIT (n = 10) participated in dedicated SIT, HIIT, and LIT training programs, respectively. SIT included 30-second all-out repetitions, HIIT included 3-minute high-intensity repetitions, LIT performed with intensity at the first ventilatory threshold. Throughout five weeks, participants in all groups underwent three weekly training sessions. Preceding and following the experiment, participants underwent an incremental test and a VO2max verification test. Additionally, serum concentrations of lectin-like oxidised lowdensity lipoprotein receptor-1 (LOX-1) and oxidised low-density lipoprotein (ox-LDL) were measured before the incremental test.
Results:
Following the conclusion of the experiment, notable mixed effects were observed. Specifically, statistically significant increases were identified in VO2max, with a 14.2% enhancement in the POL group and a 9.5% improvement in the HIIT group. Moreover, there were substantial reductions in LOX-1 levels, demonstrating a 51.5% decrease in the POL group and a 61.1% decrease in the HIIT group.
Conclusions:
The findings led to the conclusion that both the POL and long interval HIIT programs were effective in enhancing VO2max and lowering serum levels of LOX-1 among physically active individuals.
REFERENCES (47)
1.
Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Asumi M, Sugawara A, Totsuka K, Shimano H, Ohashi Y, Yamada N, Sone H. Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis. JAMA. 2009;301(19): 2024–2035; doi: 10.1001/jama.2009.681.
2.
Jones S, Tillin T, Williams S, Coady E, Chaturvedi N, Hughes AD. Assessment of exercise capacity and oxygen consumption using a 6 min stepper test in older adults. Front Physiol. 2017;8:408; doi: 10.3389/fphys.2017.00408.
3.
Meyer T, Auracher M, Heeg K, Urhausen A, Kindermann W. Effectiveness of low-intensity endurance training. Int J Sports Med. 2007;28(1):33–9; doi: 10.1055/s-2006-924037.
4.
Gist NH, Fedewa MV, Dishman RK, Cureton KJ. Sprint interval training effects on aerobic capacity: a systematic review and meta-analysis. Sports Med. 2014;44(2):269–79; doi: 10.1007/s40279- 013-0115-0.
5.
Rosenblat MA, Perrotta AS, Thomas SG. Effect of high-intensity interval training versus sprint interval training on time-trial performance: a systematic review and meta-analysis. Sports Med. 2020;50(6):1145–61; doi: 10.1007/s40279-020- 01264-1.
6.
Buchheit M, Laursen PB. High-intensity interval training, solutions to the programming puzzle: Part I: cardiopulmonary emphasis. Sports Med. 2013;43(5):313–38; doi: 10.1007/s40279-013- 0029-x.
7.
Buchheit M, Laursen PB. High-intensity interval training, solutions to the programming puzzle. Part II: anaerobic energy, neuromuscular load, and practical applications. Sports Med. 2013; 43(10):927–54; doi: 10.1007/s40279-013-0066-5.
8.
McKay BR, Paterson DH, Kowalchuk JM. Effect of short-term high-intensity interval training vs. continuous training on O2 uptake kinetics, muscle deoxygenation, and exercise performance. J Appl Physiol (1985). 2009;107(1):128–38; doi: 10.1152/ japplphysiol.90828.2008.
9.
Danek N, Smolarek M, Michalik K, Zatoń M. Comparison of acute responses to two different cycling sprint interval exercise protocols with different recovery durations. Int J Environ Res Public Health. 2020;17(3):1026; doi: 10.3390/ijerph17 031026.
10.
Purnomo E, Arovah NI, Sumaryanto S. Acute and adaptation effect of high-intensity interval training on testosterone, cortisol and performance among collegiate running athletes. Hum Mov. 2023;24(3):131–8; doi: 10.5114/hm.2023.125928.
11.
Rosenblat MA, Perrotta AS, Vicenzino B. Polarized vs. threshold training intensity distribution on endurance sport performance: a systematic review and meta-analysis of randomized controlled trials. J Strength Cond Res. 2019;33(12):3491– 500; doi: 10.1519/JSC.0000000000002618.
12.
Stöggl T, Sperlich B. Polarized training has greater impact on key endurance variables than threshold, high intensity, or high volume training. Front Physiol. 2014;5:33; doi: 10.3389/fphys.2014.00 033.
13.
Hebisz R, Hebisz P, Danek N, Michalik K, Zatoń M. Predicting changes in maximal oxygen uptake in response to polarized training (sprint interval training, high-intensity interval training, and endurance training) in mountain bike cyclists. J Strength Cond Res. 2022;36(6):1726–30; doi: 10.1519/JSC.0000000000003619.
14.
Röhrken G, Held S, Donath L. Six weeks of polarized versus moderate intensity distribution: a pilot intervention study. Front Physiol. 2020; 11:534688; doi: 10.3389/fphys.2020.534688.
15.
Neal CM, Hunter AM, Brennan L, O’Sullivan A, Hamilton DL, De Vito G, Galloway SDR. Six weeks of a polarized training-intensity distribution leads to greater physiological and performance adaptations than a threshold model in trained cyclists. J Appl Physiol (1985). 2013;114(4): 461–71; doi: 10.1152/japplphysiol.00652.2012.
16.
Hebisz P, Hebisz R, Zatoń M, Ochmann B, Mielnik N. Concomitant application of sprint and highintensity interval training on maximal oxygen uptake and work output in well-trained cyclists. Eur J Appl Physiol. 2016;116(8):1495–502; doi: 10.1007/s00421-016-3405-z.
17.
Poznyak AV, Nikiforov NG, Markin AM, Kashirskikh DA, Myasoedova VA, Gerasimova EV, Orekhov AN. Overview of oxLDL and its impact on cardiovascular health: focus on atherosclerosis. Front Pharmacol. 2021;11:613780; doi: 10.3389/ fphar.2020.613780.
18.
Leopold JA, Loscalzo J. Oxidative mechanisms and atherothrombotic cardiovascular disease. Drug Discov Today Ther Strateg. 2008;5(1):5–13; doi: 10.1016/j.ddstr.2008.02.001.
19.
Hong CG, Florida E, Li H, Parel PM, Mehta NN, Sorokin AV. Oxidized low-density lipoprotein associates with cardiovascular disease by a vicious cycle of atherosclerosis and inflammation: a systematic review and meta-analysis. Front Cardiovasc Med. 2023;9:1023651; doi: 10.3389/fcvm. 2022.1023651.
20.
Tiainen S, Kiviniemi A, Hautala A, Huikuri H, Ukkola O, Tokola K, Tulppo M, Vasankari T. Effects of a two-year home-based exercise training program on oxidized LDL and HDL lipids in coronary artery disease patients with and without type-2 diabetes. Antioxidants. 2018;7(10):144; doi: 10.3390/antiox7100144.
21.
Yang J, Cao RY, Gao R, Mi Q, Dai Q, Zhu F. Physical exercise is a potential “medicine” for atherosclerosis. Adv Exp Med Biol. 2017;999:269–86; doi: 10.1007/978-981-10-4307-9_15.
22.
Taylor BA, Zaleski AL, Capizzi JA, Ballard KD, Troyanos C, Baggish AL, D’Hemecourt PA, Dada MR, Thompson PD. Influence of chronic exercise on carotid atherosclerosis in marathon runners. BMJ Open. 2014;4(2):e004498; doi: 10.1136/ bmjopen-2013-004498.
23.
Jamnick NA, Botella J, Pyne DB, Bishop DJ. Manipulating graded exercise test variables affects the validity of the lactate threshold and VO2peak. PLOS ONE. 2018;13(7):e0199794; doi: 10.1371/ journal.pone.0199794.
24.
Bentley DJ, Newell J, Bishop D. Incremental exercise test design and analysis: implications for performance diagnostics in endurance athletes. Sports Med. 2007;37(7):575–86; doi: 10.2165/ 00007256-200737070-00002.
25.
Lounana J, Campion F, Noakes TD, Medelli J. Relationship between %HRmax, %HR reserve, %VO2max, and %VO2 reserve in elite cyclists. Med Sci Sports Exerc. 2007;39(2):350–7; doi: 10.1249/ 01.mss.0000246996.63976.5f.
26.
Helgerud J, Høydal K, Wang E, Karlsen T, Berg P, Bjerkaas M, Simonsen T, Helgesen C, Hjorth N, Bach R, Hoff J. Aerobic high-intensity intervals improve VO2max more than moderate training. Med Sci Sports Exerc. 2007;39(4):665–71; doi: 10.1249/mss.0b013e3180304570.
27.
Astorino TA, deRevere J, Anderson T, Kellogg E, Holstrom P, Ring S, Ghaseb N. Change in VO2max and time trial performance in response to highintensity interval training prescribed using ventilatory threshold. Eur J Appl Physiol. 2018;118(9): 1811–20; doi: 10.1007/s00421-018-3910-3.
28.
Esfarjani F, Laursen PB. Manipulating high-intensity interval training: effects on VO2max, the lactate threshold and 3000 m running performance in moderately trained males. J Sci Med Sport. 2007;10(1):27–35; doi: 10.1016/j.jsams.2006. 05.014.
29.
Macpherson REK, Hazell TJ, Olver TD, Paterson DH, Lemon PWR. Run sprint interval training improves aerobic performance but not maximal cardiac output. Med Sci Sports Exerc. 2011; 43(1):115–22; doi: 10.1249/MSS.0b013e3181e5 eacd.
30.
Sökmen B, Witchey RL, Adams GM, Beam WC. Effects of sprint interval training with active recovery vs. endurance training on aerobic and anaerobic power, muscular strength, and sprint ability. J Strength Cond Res. 2018;32(3):624–31; doi: 10.1519/JSC.0000000000002215.
31.
Bailey SJ, Wilkerson DP, Dimenna FJ, Jones AM. Influence of repeated sprint training on pulmonary O2 uptake and muscle deoxygenation kinetics in humans. J Appl Physiol (1985). 2009;106(6): 1875–87; doi: 10.1152/japplphysiol.00144.2009.
32.
Zelt JGE, Hankinson PB, Foster WS, Williams CB, Reynolds J, Garneys E, Tschakovsky ME, Gurd BJ. Reducing the volume of sprint interval training does not diminish maximal and submaximal performance gains in healthy men. Eur J Appl Physiol. 2014;114(11):2427–36; doi: 10.1007/s00421-014- 2960-4.
33.
Vollaard NBJ, Metcalfe RS, Williams S. Effect of number of sprints in an SIT session on change in VO2max: a meta-analysis. Med Sci Sports Exerc. 2017;49(6):1147–56; doi: 10.1249/MSS.000000 0000001204.
34.
Hawley JA, Stepto NK. Adaptations to training in endurance cyclists: implications for performance. Sports Med. 2001;31(7):511–20; doi: 10.2165/00007256-200131070-00006.
35.
Lloyd JMC, Morris MG, Jakeman JR. Impact of time and work: rest ratio matched sprint interval training programmes on performance: a randomized controlled trial. J Sci Med Sport. 2017; 20(11):1034–8; doi: 10.1016/j.jsams.2017.03.020.
36.
Till K, Lloyd RS, McCormack S, Williams G, Baker J, Eisenmann JC. Optimising long-term athletic development: an investigation of practitioners’ knowledge, adherence, practices and challenges. PLOS ONE. 2022;17(1):e0262995; doi: 10.1371/ journal.pone.0262995.
37.
Høydal KL. Effects of exercise intensity on VO2max in studies comparing two or more exercise intensities: a meta-analysis. Sport Sci Health. 2017;13: 239–52; doi: 10.1007/s11332-017-0367-4.
38.
Park JH, Park H, Lim ST, Park JK. Effects of a 12- week healthy-life exercise program on oxidized low-density lipoprotein cholesterol and carotid intima-media thickness in obese elderly women. J Phys Ther Sci. 2015;27(5):1435–9; doi: 10.1589/ jpts.27.1435.
39.
Yol Y, Turgay F, Yigittürk O, Aşıkovalı S, Durmaz B. The effects of regular aerobic exercise training on blood nitric oxide levels and oxidized LDL and the role of eNOS intron 4a/b polymorphism. Biochim Biophys Acta Mol Basis Dis. 2020; 1866(12):165913; doi: 10.1016/j.bbadis.2020.16 5913.
40.
Barreto J, Karathanasis SK, Remaley A, Sposito AC. Role of LOX-1 (lectin-like oxidized low-density lipoprotein receptor 1) as a cardiovascular risk predictor: mechanistic insight and potential clinical use. Arterioscler Thromb Vasc Biol. 2021; 41(1):153–66; doi: 10.1161/ATVBAHA.120.315421.
41.
Zhao ZW, Xu YW, Li SM, Guo JJ, Sun JM, Hong JC, Chen L-L. Baseline serum sLOX-1 concentrations are associated with 2-year major adverse cardiovascular and cerebrovascular events in patients after percutaneous coronary intervention. Dis Markers. 2019;2019:4925767; doi: 10.1155/ 2019/4925767.
42.
Wilhelm EN, González-Alonso J, Parris C, Rakobowchuk M. Exercise intensity modulates the appearance of circulating microvesicles with proangiogenic potential upon endothelial cells. Am J Physiol Heart Circ Physiol. 2016;311(5): H1297–H1310; doi: 10.1152/ajpheart.00516.2016.
43.
Thijssen DHJ, Dawson EA, Black MA, Hopman MTE, Cable NT, Green DJ. Brachial artery blood flow responses to different modalities of lower limb exercise. Med Sci Sports Exerc. 2009;41(5): 1072–9; doi: 10.1249/MSS.0b013e3181923957.
44.
Gurd BJ, Perry CGR, Heigenhauser GJF, Spriet LL, Bonen A. High-intensity interval training increases SIRT 1 activity in human skeletal muscle. Appl Physiol Nutr Metab. 2010;35(3):350–7; doi: 10.1139/H10-030.
45.
Hung CH, Chan SH, Chu PM, Tsai KL. Homocysteine facilitates LOX-1 activation and endothelial death through the PKC and SIRT 1/HSF1 mechanism: relevance to human hyperhomocysteinemia. Clin Sci (Lond). 2015;129(6):477–87; doi: 10.1042/CS20150127.
46.
Rhibi F, Zouhal H, Lira FS, Ouerghi N, Prioux J, Besbes S, Tijani JM, Hackney AC, Abderrahman AB. Inflammatory cytokines and metabolic responses to high-intensity intermittent training: effect of the exercise intensity. Biol Sport. 2022; 39(2):263–72; doi: 10.5114/biolsport.2022.104914.
47.
Zhao XQ, Zhang MW, Wang F, Zhao YX, Li JJ, Wang XP, Bu PL, Yang JM, Liu XL, Zhang MX, Gao F, Zhang C, Zhang Y. CRP enhances soluble LOX-1 release from macrophages by activating TNF- converting enzyme. J Lipid Res. 2011;52(5): 923–33; doi: 10.1194/jlr.M015156.
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